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{"id":1222,"date":"2024-10-02T17:39:00","date_gmt":"2024-10-02T15:39:00","guid":{"rendered":"https:\/\/prezode.grauw.dev\/?p=1222"},"modified":"2025-04-22T15:34:28","modified_gmt":"2025-04-22T13:34:28","slug":"first-four-pepr-projects-have-been-selected","status":"publish","type":"post","link":"https:\/\/prezode.grauw.dev\/en\/first-four-pepr-projects-have-been-selected\/","title":{"rendered":"Overview of the first four PEPR projects"},"content":{"rendered":"\n<p><strong>On September 30, 2024, the four projects selected in the first phase of the PEPR PREZODE were showcased during the event \u201c<a href=\"https:\/\/agriculture.gouv.fr\/france-2030-point-detape-de-la-strategie-maladies-infectieuses-et-emergentes-mie-et-menaces\" target=\"_blank\" rel=\"noreferrer noopener\">Acceleration Strategy Day for Emerging Infectious Diseases \u2013 NRBC Threats: 3 Years of Actions Taken to Be Ready for Tomorrow<\/a>&#8220;.<\/strong><\/p>\n\n\n\n<p>These projects, covering a budget of 9 M\u20ac, seek to better understand the links between human activities, global changes, and the mechanisms of zoonotic disease emergence. The selected projects address multiple pathogens, vectors, emergence factors, and geographical study sites, including overseas territories.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>AMAZED<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Monitoring arbovirus emergence using a \u201cOne Health\u201d approach\u00a0<br><\/h3>\n\n\n\n<p>The AMAZED project will investigate the mechanisms of arbovirus emergence using a \u201cOne Health\u201d approach across several overseas territories, including French Guiana, the Caribbean, the South Pacific, as well as in Cameroon and mainland France. It will assess the impact of anthropogenic changes on the emergence of vector-borne viruses (including climate change and human encroachment into natural areas through resource exploitation and agricultural expansion). By comparing tropical, insular, continental, and temperate contexts, the project aims to test hypotheses and evaluate risks associated with entomological and human factors. The expected outcomes could lead to the development of strategies and tools to prevent the emergence of these viruses and thus mitigate the risks of related epidemics.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>ARCHE<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Focus on the Crimean-Congo Hemorrhagic Fever virus emergence determinants<\/h3>\n\n\n\n<p>The ARCHE project aims to understand the determinants of the emergence of the Crimean-Congo Hemorrhagic Fever virus (CCHFV \u2013 transmitted by ticks to humans and animals) in different regions of southern France. The expected results will help identify factors that promote both the emergence and transmission risks, improve virus detection methods, estimate the circulation of CCHFV and other orthonairoviruses, model its transmission dynamics, and co-design and disseminate preventive actions through socio-ecological and participatory science approaches.\u00a0<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>ZOOCAM<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Interdisciplinary research on zoonotic pathogens in the Camargue region<br><\/h3>\n\n\n\n<p>The ZOOCAM project aims to understand: <\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>1) the dynamics of circulating\/emerging zoonotic agents in the Camargue; <\/li>\n\n\n\n<li>2) the human and environmental factors influencing the spread of zoonotic agents, particularly species barrier crossing; <\/li>\n\n\n\n<li>3) whether current and emerging zoonotic risks can be modeled\/predicted; <\/li>\n\n\n\n<li>4) the risk perception by local stakeholders. <\/li>\n<\/ul>\n\n\n\n<p>The project seeks to unite health-environment research in the Camargue with an integrative and interdisciplinary approach to provide concrete responses to local actors. The consortium will engage stakeholders to co-develop an integrated adaptive management approach for zoonoses. The expected results will support the development of tools for training, awareness-raising workshops, land-use planning, and multi-stakeholder workshops aimed at improving zoonosis surveillance and assessment methods.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>ZOOFLU<\/strong><\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Improving the surveillance of highly pathogenic avian influenza viruses (HPAIV)<\/h3>\n\n\n\n<p>Finally, the, ZOOFLU project aims at unlocking the emergence of zoonotic highly pathogenic avian influenza viruses (HPAIV) at the wildlife-domestic animal-human interface. More specifically, this project will improve surveillance, identify how the HPAIV evolution affects their transmission and ability to cross species barriers, and characterize the social factors enabling the most appropriate vaccination strategies to be evaluated.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>A focus on three axes:&nbsp;<\/strong><\/h2>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Characterization and role of hosts, reservoirs, and vectors, and their interactions in the evolution, circulation, transmission, and emergence of zoonotic pathogens in the context of global changes.<\/li>\n\n\n\n<li>Characterization of sociological, economic, and environmental dimensions in the evolution, circulation, and emergence of zoonotic pathogens at the human\/animal\/environment interface in the context of global change.<\/li>\n\n\n\n<li>Characterization and quantification of cascade effects between human activities, global changes, socio-economic activities, the structuring of ecological communities, and zoonotic emergence risks.<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>On September 30, 2024, the four projects selected in the first phase of the PEPR PREZODE were showcased during the event \u201cAcceleration Strategy Day for Emerging Infectious Diseases \u2013 NRBC Threats: 3 Years of Actions Taken to Be Ready for Tomorrow&#8220;. These projects, covering a budget of 9 M\u20ac, seek to better understand the links<a href=\"https:\/\/prezode.grauw.dev\/en\/first-four-pepr-projects-have-been-selected\/\">Continue reading <span class=\"sr-only\">&#8220;Overview of the first four PEPR projects&#8221;<\/span><\/a><\/p>\n","protected":false},"author":2,"featured_media":1193,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[38],"tags":[],"news_type":[10],"class_list":["post-1222","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-programmes","news_type-article"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Overview of the first four PEPR projects - PP - Prezode<\/title>\n<meta name=\"description\" content=\"On September 30, 2024, the four projects selected in the first phase of the PEPR PREZODE. 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